Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554717 | 1.00 | SPHK1 (0.46) | SPHK1SPHK2GAAMAPTAPP | |
| SCHEMBL9270748 | 0.87 | APP (0.49) | GAAMAPTAPPKDM4ENPC1 | |
| SCHEMBL9270753 | 0.87 | APP (0.49) | GAAMAPTAPPKDM4ENPC1 | |
| SCHEMBL8554126 | 0.84 | MAPT (0.41) | SPHK1GAAMAPT | |
| SCHEMBL8554123 | 0.84 | MAPT (0.41) | SPHK1GAAMAPT | |
| SCHEMBL8554845 | 0.82 | APP (0.51) | GAAMAPTAPPKDM4ENPC1 | |
| SCHEMBL8553099 | 0.82 | APP (0.51) | GAAMAPTAPPKDM4ENPC1 | |
| SCHEMBL5946763 | 0.82 | APP (0.51) | GAAMAPTAPPKDM4ENPC1 | |
| SCHEMBL8547227 | 0.82 | ATP4A (0.46) | MAPTAPP | |
| SCHEMBL8551522 | 0.82 | CYP3A4 (0.42) | GAAMAPTAPPKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440061-B1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KK (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5284599-A | Benzothiazole with alkyl group having asymmetric carbon connected to halogen; improved response | CANON KABUSHIKI KAISHA (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5236619-A | Benzothiazoles | CANON KABUSHIKI KAISHA (JP) | 1993-08-17 | — | — | US | disclosed |
| EP-0440061-A1 | Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus | CANON KABUSHIKI KAISHA (JP) | 1991-08-07 | — | — | EP | disclosed |