SCHEMBL8553099

SCHEMBL8553099

CCCCCCCCc1ccc(-c2nc3ccc(CCCCCC)cc3s2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.51
KDM4E B2RXH2 4/20 0.50
RAB9A P51151 4/20 0.50
MAPT P10636 4/20 0.50
NPC1 O15118 3/20 0.50
GAA P10253 3/20 0.50
GLA P06280 2/20 0.50
ALDH1A1 P00352 2/20 0.49
HPGD P15428 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
SNCA P37840 1/20 0.48
RARB P10826 4/20 0.46
MEN1 O00255 1/20 0.46
RARA P10276 1/20 0.46
MTOR P42345 1/20 0.46
KMT2A Q03164 1/20 0.46
CASP3 P42574 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8554845 1.00 APP (0.51) APPKDM4ERAB9AMAPTNPC1
SCHEMBL5946763 1.00 APP (0.51) APPKDM4ERAB9AMAPTNPC1
SCHEMBL8551625 0.99 APP (0.50) APPKDM4ERAB9AMAPTNPC1
SCHEMBL5946928 0.93 CASP3 (0.46) APPKDM4ERAB9AMAPTNPC1
SCHEMBL11335376 0.92 APP (0.63) APPKDM4ERAB9AMAPTNPC1
SCHEMBL8218536 0.92 MAPT (0.56) APPKDM4ERAB9AMAPTNPC1
SCHEMBL8554888 0.92 MAPT (0.56) APPKDM4ERAB9AMAPTNPC1
SCHEMBL5946699 0.90 APP (0.45) APPKDM4ERAB9AMAPTNPC1
SCHEMBL8551451 0.90 RARB (0.56) APPKDM4ERAB9AMAPTNPC1
SCHEMBL5946619 0.89 ATP4A (0.56) APPRAB9AMAPTGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4029984-A None JP disclosed
JP-5039482-A None JP disclosed
EP-0440061-B1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KK (JP) 1998-04-01 EP disclosed
EP-0499252-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1996-09-11 EP disclosed
EP-0499222-B1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1995-05-03 EP disclosed
US-5284599-A Benzothiazole with alkyl group having asymmetric carbon connected to halogen; improved response CANON KABUSHIKI KAISHA (JP) 1994-02-08 US disclosed
US-5268123-A Structure containing thiophene and benzene rings CANON KABUSHIKI KAISHA (JP) 1993-12-07 US disclosed
US-5262083-A Oxazole or thiazole compounds CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
US-5236619-A Benzothiazoles CANON KABUSHIKI KAISHA (JP) 1993-08-17 US disclosed
JP-H0539482-A LIQUID CRYSTAL COMPOSITION, ITS USAGE AND LIQUID CRYSTAL ELEMENT AND DISPLAY USING THE SAME CANON INC 1993-02-19 JP disclosed
EP-0499222-A1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed
EP-0499252-A1 Liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1992-08-19 EP disclosed
JP-H0429984-A LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME AND LIQUID CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE USING THE SAME CANON INC 1992-01-31 JP disclosed
EP-0440061-A1 Mesomorphic compound, liquid crystal composition containing same, liquid crystal device using same and display apparatus CANON KABUSHIKI KAISHA (JP) 1991-08-07 EP disclosed