Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | PNMT | P11086 | 6/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215164 | 0.89 | CYP3A4 (0.53) | DRD2DRD3PNMTGRM2CYP3A4 | |
| SCHEMBL11210812 | 0.87 | CYP3A4 (0.51) | DRD2DRD3PNMTCYP3A4CYP2C8 | |
| SCHEMBL8552658 | 0.82 | KDM4E (0.56) | GRM2TSHRHSD17B10CYP3A4CYP2C8 | |
| SCHEMBL11139692 | 0.79 | CYP3A4 (0.49) | DRD2DRD3GRM2TSHRHSD17B10 | |
| SCHEMBL11141207 | 0.79 | CYP3A4 (0.49) | DRD2DRD3GRM2TSHRHSD17B10 | |
| SCHEMBL11142580 | 0.79 | CYP3A4 (0.49) | DRD2DRD3GRM2TSHRHSD17B10 | |
| SCHEMBL11139566 | 0.78 | MCHR1 (0.48) | DRD2DRD3TSHRHSD17B10CYP3A4 | |
| SCHEMBL6838956 | 0.77 | PNMT (0.46) | PNMTCYP3A4CYP2C8S1PR3CYP2D6 | |
| SCHEMBL6839687 | 0.77 | PNMT (0.46) | PNMTCYP3A4CYP2C8S1PR3CYP2D6 | |
| SCHEMBL11211912 | 0.77 | DRD2 (0.46) | DRD2DRD3PNMTCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |