Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | FPR2 | P25090 | 6/20 | 0.37 |
| ▸ | FPR1 | P21462 | 5/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555027 | 0.86 | HDAC6 (0.43) | HDAC6HDAC1HDAC8FPR2FPR1 | |
| SCHEMBL8552381 | 0.79 | MCHR1 (0.47) | HDAC6SSTR4CCR2SSTR1 | |
| SCHEMBL8670578 | 0.77 | HDAC6 (0.40) | HDAC6HDAC1HDAC8FPR2FPR1 | |
| SCHEMBL8670568 | 0.77 | SSTR4 (0.46) | HDAC6HDAC1HDAC8SSTR4SSTR1 | |
| SCHEMBL8670567 | 0.77 | MCHR1 (0.39) | HDAC6HDAC1HDAC8FPR2FPR1 | |
| SCHEMBL7806223 | 0.74 | F10 (0.43) | HDAC6HDAC1HDAC8 | |
| SCHEMBL8595364 | 0.70 | MCHR1 (0.47) | HDAC6FPR2FPR1CCR2 | |
| SCHEMBL8554800 | 0.69 | MCHR1 (0.46) | HDAC6FPR2FPR1CCR2 | |
| SCHEMBL19471943 | 0.67 | HDAC1 (0.61) | HDAC6HDAC1HDAC8FPR2FPR1 | |
| SCHEMBL19471942 | 0.67 | HDAC1 (0.61) | HDAC6HDAC1HDAC8FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863894-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1998-09-16 | — | — | EP | disclosed |
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| WO-1997020838-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1997-06-12 | — | — | WO | disclosed |