Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552381 | 0.92 | MCHR1 (0.47) | MCHR1HDAC6ROCK2SSTR4DRD2 | |
| SCHEMBL8670568 | 0.86 | SSTR4 (0.46) | MCHR1HDAC6ROCK2HDAC1HDAC8 | |
| SCHEMBL8670578 | 0.84 | HDAC6 (0.40) | MCHR1HDAC6ROCK2HDAC1HDAC8 | |
| SCHEMBL8595364 | 0.84 | MCHR1 (0.47) | MCHR1HDAC6ROCK2DRD2DRD3 | |
| SCHEMBL8554800 | 0.83 | MCHR1 (0.46) | MCHR1HDAC6ROCK2DRD2DRD3 | |
| SCHEMBL8552408 | 0.79 | MCHR1 (0.47) | MCHR1HDAC6ROCK2DRD2DRD3 | |
| SCHEMBL8555027 | 0.77 | HDAC6 (0.43) | HDAC6ROCK2HDAC1HDAC8DRD2 | |
| SCHEMBL8554783 | 0.77 | HDAC6 (0.39) | HDAC6HDAC1HDAC8SSTR4FPR1 | |
| SCHEMBL8662424 | 0.74 | MCHR1 (0.39) | MCHR1DRD2DRD3KCNH2 | |
| SCHEMBL8554346 | 0.74 | MCHR1 (0.40) | MCHR1DRD2DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |