Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554783 | 0.86 | HDAC6 (0.39) | HDAC6HDAC1HDAC8FPR2FPR1 | |
| SCHEMBL8552381 | 0.79 | MCHR1 (0.47) | HDAC6ROCK2DRD2DRD3 | |
| SCHEMBL6530315 | 0.78 | CYP2D6 (0.50) | HDAC6HDAC1HDAC8CYP2D6CYP2C19 | |
| SCHEMBL8670568 | 0.77 | SSTR4 (0.46) | HDAC6HDAC1HDAC8ROCK2POLB | |
| SCHEMBL8670578 | 0.77 | HDAC6 (0.40) | HDAC6HDAC1HDAC8ROCK2FPR2 | |
| SCHEMBL8670567 | 0.77 | MCHR1 (0.39) | HDAC6HDAC1HDAC8ROCK2FPR2 | |
| SCHEMBL13116279 | 0.72 | CYP2D6 (0.52) | HDAC6HDAC1HDAC8CYP2D6CYP2C19 | |
| SCHEMBL8863137 | 0.72 | FPR2 (0.45) | HDAC6HDAC1HDAC8FPR2FPR1 | |
| SCHEMBL2289335 | 0.71 | ALDH1A1 (0.46) | HDAC6HDAC1HDAC8CYP2D6CYP2C19 | |
| SCHEMBL11031414 | 0.71 | HDAC6 (0.82) | HDAC6HDAC1HDAC8ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863894-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1998-09-16 | — | — | EP | disclosed |
| US-5705456-A | AZETIDIN-2-ONES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| WO-1997020838-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | ZENECA LIMITED (GB) | 1997-06-12 | — | — | WO | disclosed |