Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150045 | 0.95 | ALDH1A1 (0.78) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL30416948 | 0.88 | ALDH1A1 (0.72) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL6639178 | 0.88 | ALDH1A1 (0.72) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL2149364 | 0.84 | ALDH1A1 (0.81) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL5544569 | 0.84 | ALDH1A1 (0.81) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL5503439 | 0.84 | ALDH1A1 (0.81) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL25320405 | 0.83 | ALDH1A1 (0.84) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL12124769 | 0.83 | HTR1A (0.82) | — | |
| SCHEMBL5545702 | 0.83 | ALDH1A1 (0.84) | ALDH1A1NPSR1TSHRUSP2HPGD | |
| SCHEMBL14288460 | 0.83 | ALDH1A1 (0.84) | ALDH1A1NPSR1TSHRUSP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564358-B1 | 3-aminochromane spiro derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5420150-A | Antidepressants and treatment of anxiety | GUILLAUMET GERALD (FR) | 1995-05-30 | — | — | US | disclosed |
| US-5397783-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1995-03-14 | — | — | US | disclosed |
| US-5376661-A | Psychological disorders | ADIR ET COMPAGNIE (FR) | 1994-12-27 | — | — | US | disclosed |
| EP-0564358-A1 | 3-aminochromane spiro derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-10-06 | — | — | EP | disclosed |