Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815554 | 0.89 | GAA (0.72) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11550281 | 0.87 | GAA (0.70) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1107148 | 0.87 | GAA (0.70) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL377638 | 0.87 | GAA (0.65) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9267668 | 0.87 | GAA (0.70) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3495434 | 0.86 | PLA2G4B (0.68) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7692043 | 0.85 | GAA (0.68) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14402167 | 0.85 | GAA (0.68) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL434786 | 0.85 | GAA (0.68) | GAANPSR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10867147 | 0.85 | GAA (0.68) | GAANPSR1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |