Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | JAK2 | O60674 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4395319 | 0.86 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL1592594 | 0.84 | RXFP1 (0.62) | ALDH1A1L3MBTL1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL22750815 | 0.82 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL14053819 | 0.82 | RXFP1 (0.60) | ALDH1A1L3MBTL1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL12852574 | 0.82 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL25696684 | 0.82 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL7143553 | 0.82 | LCK (0.59) | ALDH1A1L3MBTL1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL3585209 | 0.81 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL8556409 | 0.79 | NPC1 (0.60) | ALDH1A1L3MBTL1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL8554826 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7089946-A | — | — | None | — | — | JP | disclosed |
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2025-03-13 | — | — | US | disclosed |
| CN-119421877-A | Substituted heterocyclic compounds as HSET inhibitors | 默克专利股份公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4463444-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2024-11-20 | — | — | EP | disclosed |
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |
| WO-2012016362-A1 | Β-SECRETASE INHIBITORS FOR TREATING ALZHEIMER'S DISEASE AND USES THEREOF | 中国人民解放军军事医学科学院毒物药物研究所 (CN) | 2012-02-09 | — | — | WO | disclosed |
| US-20110294758-A1 | NOVEL ACTIVATORS OF GLUCOKINASE | METABASIS THERAPEUTICS, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| EP-0639574-B1 | 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms | LUCKY LTD (KR) | 1998-06-10 | — | — | EP | disclosed |
| US-5514643-A | FUNGICIDES FOR PLANTS | LUCKY LTD. (KR) | 1996-05-07 | — | — | US | disclosed |
| JP-H0789946-A | NOVEL 2-AMINOTHIAZOLECARBOXAMIDE DERIVATIVE, ITS PRODUCTION AND ANTIBACTERIAL AGENT FOR PHYTOPATHOGENIC ORGANISMS | LUCKY CO LTD | 1995-04-04 | — | — | JP | disclosed |
| EP-0639574-A1 | 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms | LUCKY LTD. (KR) | 1995-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084074-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | VHL, CDKN1A, CCNI | ALDH1A1 1680/4885L3MBTL1 2054/4885TSHR 3700/4885 |
| US-20110294758-A1 | NOVEL ACTIVATORS OF GLUCOKINASE | GCKR, GCK, HK1 | ALDH1A1 2389/4885L3MBTL1 3980/4885TSHR 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.