Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8556705 | 0.98 | NPC1 (0.58) | NPC1ALDH1A1HPGDTSHRMAPK14 | |
| SCHEMBL2076096 | 0.86 | ALDH1A1 (0.65) | NPC1ALDH1A1HPGDTSHRMAPK14 | |
| SCHEMBL13576262 | 0.84 | MAPK14 (0.48) | NPC1ALDH1A1HPGDMAPK14CCNA2 | |
| SCHEMBL8556702 | 0.84 | MAPK14 (0.48) | NPC1ALDH1A1HPGDMAPK14CCNA2 | |
| SCHEMBL8552123 | 0.81 | CCNA2 (0.48) | NPC1ALDH1A1HPGDTSHRMAPK14 | |
| SCHEMBL27643470 | 0.80 | MAPK14 (0.45) | NPC1ALDH1A1HPGDMAPK14CCNA2 | |
| SCHEMBL8554963 | 0.79 | ALDH1A1 (0.55) | NPC1ALDH1A1HPGDTSHRCCNA2 | |
| SCHEMBL3577082 | 0.79 | ALDH1A1 (0.62) | NPC1ALDH1A1HPGDTSHRPKM | |
| SCHEMBL347225 | 0.79 | NPC1 (0.53) | NPC1ALDH1A1HPGDTSHRPKM | |
| SCHEMBL22750815 | 0.78 | ALDH1A1 (0.53) | NPC1ALDH1A1HPGDTSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015069011-A1 | NOVEL COMPOUND, METHOD FOR PREPARATION THEREOF, AND ANTIFUNGAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2015-05-14 | — | — | WO | disclosed |
| CN-102516240-A | Heteroaryl-ureas and their use as glucokinase activators | NOVO NORDISK AS | 2012-06-27 | — | — | CN | disclosed |
| CN-1910166-B | Heteroaryl ureas and their use as glucokinase activators | NOVO NORDISK AS | 2012-01-04 | — | — | CN | disclosed |
| CN-1910166-A | Heteroaryl ureas and their use as glucokinase activators | NOVO NORDISK AS (DK) | 2007-02-07 | — | — | CN | disclosed |
| EP-0639574-B1 | 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms | LUCKY LTD (KR) | 1998-06-10 | — | — | EP | disclosed |
| US-5514643-A | FUNGICIDES FOR PLANTS | LUCKY LTD. (KR) | 1996-05-07 | — | — | US | disclosed |
| EP-0639574-A1 | 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms | LUCKY LTD. (KR) | 1995-02-22 | — | — | EP | disclosed |