Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375098 | 0.76 | CA12 (0.39) | CA12CA1CA2CA9MAOA | |
| SCHEMBL7376303 | 0.76 | CA12 (0.39) | CA12CA1CA2CA9MAOA | |
| SCHEMBL6989337 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7844777 | 0.71 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL7373154 | 0.70 | ITGB3 (0.54) | ITGB3ITGA2BMIF | |
| SCHEMBL7378707 | 0.70 | ITGB3 (0.37) | ITGB3ITGA2B | |
| SCHEMBL7374519 | 0.69 | ITGB3 (0.39) | ITGB3ITGA2B | |
| SCHEMBL7375675 | 0.68 | ITGB3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL7377212 | 0.68 | ITGB3 (0.45) | ITGB3ITGA2B | |
| SCHEMBL8353290 | 0.68 | CA12 (0.43) | CA12CA1CA2CA9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996038426-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-12-05 | — | — | WO | disclosed |