Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.48 |
| ▸ | YAP1 | P46937 | 3/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556312 | 0.81 | PRMT5 (0.51) | PRMT5YAP1GPR119 | |
| SCHEMBL8552560 | 0.76 | NPY1R (0.45) | PRMT5TDP1 | |
| SCHEMBL7691262 | 0.76 | NPY1R (0.56) | — | |
| SCHEMBL8555211 | 0.75 | GPR119 (0.45) | PRMT5GPR119FAAH | |
| SCHEMBL7686494 | 0.74 | YAP1 (0.48) | PRMT5YAP1GPR119LMNATP53 | |
| SCHEMBL8551336 | 0.74 | GPR119 (0.47) | PRMT5GPR119FAAH | |
| SCHEMBL8557780 | 0.74 | GPR119 (0.44) | PRMT5GPR119FAAH | |
| SCHEMBL3358504 | 0.73 | YAP1 (0.65) | PRMT5YAP1GPR119 | |
| SCHEMBL8552756 | 0.72 | GPR119 (0.45) | PRMT5GPR119FAAH | |
| SCHEMBL12813454 | 0.72 | YAP1 (0.66) | PRMT5YAP1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |