SCHEMBL8555317

SCHEMBL8555317

CCOC(=O)c1sc(NC(=O)OC)nc1C

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.76
HPGD P15428 7/20 0.76
TSHR P16473 2/20 0.73
NPC1 O15118 6/20 0.68
NPSR1 Q6W5P4 2/20 0.64
RXFP1 Q9HBX9 2/20 0.64
KDM4E B2RXH2 3/20 0.64
LMNA P02545 2/20 0.64
SMN1; SMN2 Q16637 7/20 0.62
HTT P42858 2/20 0.62
GAA P10253 2/20 0.61
RAB9A P51151 5/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
MAPT P10636 2/20 0.60
TP53 P04637 1/20 0.60
HSP90AA1 P07900 1/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL349175 0.86 ALDH1A1 (0.68) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL27361420 0.84 ALDH1A1 (0.74) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL7147053 0.84 ALDH1A1 (0.74) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL8556695 0.83 L3MBTL1 (0.73) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL28340135 0.82 ALDH1A1 (0.76) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL27224566 0.82 ALDH1A1 (0.76) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL7939133 0.82 ALDH1A1 (0.72) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL244627 0.82 ALDH1A1 (0.72) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL2208204 0.82 ALDH1A1 (0.72) ALDH1A1HPGDTSHRNPC1NPSR1
SCHEMBL3046343 0.81 ALDH1A1 (0.70) ALDH1A1HPGDTSHRNPC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639574-B1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD (KR) 1998-06-10 EP disclosed
US-5514643-A FUNGICIDES FOR PLANTS LUCKY LTD. (KR) 1996-05-07 US disclosed
EP-0639574-A1 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms LUCKY LTD. (KR) 1995-02-22 EP disclosed