Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557608 | 1.00 | KMT2A (0.37) | KMT2AMAPTMEN1KDM4EUSP2 | |
| SCHEMBL10513278 | 0.83 | TSHR (0.47) | KMT2AMAPTMEN1KDM4EHTT | |
| SCHEMBL10513445 | 0.83 | TSHR (0.47) | KMT2AMAPTMEN1KDM4EHTT | |
| SCHEMBL8554257 | 0.77 | TSHR (0.40) | KMT2AMAPTMEN1KDM4EHTT | |
| SCHEMBL8595054 | 0.77 | TSHR (0.40) | KMT2AMAPTMEN1KDM4EHTT | |
| SCHEMBL10506341 | 0.75 | KMT2A (0.50) | KMT2AMAPTMEN1KDM4EHTT | |
| SCHEMBL4627330 | 0.70 | TSHR (0.45) | KMT2AKDM4ETDP1POLBRARB | |
| SCHEMBL10504808 | 0.69 | ASAH1 (0.47) | KMT2AMAPTMEN1KDM4EHTT | |
| SCHEMBL10515420 | 0.68 | TSHR (0.57) | KMT2AMAPTMEN1KDM4EPOLB | |
| SCHEMBL29444061 | 0.65 | ESR1 (0.42) | KMT2AKDM4ETDP1RARBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513966-B1 | Bis-bibenzimidazole composition | ZENECA LTD (GB) | 1998-04-29 | — | — | EP | disclosed |
| US-5258524-A | Solvent extraction of zinc | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | disclosed |