Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595054 | 1.00 | TSHR (0.40) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL10513278 | 0.90 | TSHR (0.47) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL10513445 | 0.90 | TSHR (0.47) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL8598155 | 0.89 | TSHR (0.48) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL10506341 | 0.82 | KMT2A (0.50) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL10515420 | 0.77 | TSHR (0.57) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL8555403 | 0.77 | KMT2A (0.37) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL8557608 | 0.77 | KMT2A (0.37) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL10504808 | 0.73 | ASAH1 (0.47) | TSHRKMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL8598151 | 0.71 | TLR8 (0.45) | TSHRKMT2ARAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0513966-B1 | Bis-bibenzimidazole composition | ZENECA LTD (GB) | 1998-04-29 | — | — | EP | disclosed |
| US-5258524-A | Solvent extraction of zinc | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | disclosed |
| EP-0513966-A2 | Bis-bibenzimidazole composition | ZENECA LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |