Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 20/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 20/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198698 | 0.94 | ADRA1D (0.57) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6194108 | 0.93 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6201215 | 0.87 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL13939624 | 0.82 | ADRA1D (0.70) | ADRA1DADRA1AADRA1B | |
| SCHEMBL3991000 | 0.78 | ADRA1D (0.61) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6270146 | 0.77 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7518584 | 0.73 | ADRA1A (0.61) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6727770 | 0.73 | ADRA1A (0.61) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6785396 | 0.72 | ADRA1D (0.49) | ADRA1DADRA1AADRA1B | |
| SCHEMBL3985440 | 0.71 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790826-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0790826-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |