Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559312 | 0.90 | AVPR1A (0.55) | AVPR2AVPR1A | |
| SCHEMBL8556946 | 0.88 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL8557423 | 0.86 | ACHE (0.51) | AVPR2AVPR1A | |
| SCHEMBL8562058 | 0.85 | AVPR1A (0.55) | AVPR2AVPR1A | |
| SCHEMBL8562629 | 0.84 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL8563299 | 0.84 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8556851 | 0.84 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8563516 | 0.84 | AVPR2 (0.55) | AVPR2AVPR1A | |
| SCHEMBL8557995 | 0.84 | KCNJ5 (0.47) | AVPR2AVPR1A | |
| SCHEMBL8556570 | 0.82 | AVPR2 (0.56) | AVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |