Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124124 | 0.82 | ALDH1A1 (0.45) | KMT2AGAAALOX5ALDH1A1HPGD | |
| SCHEMBL1326250 | 0.80 | ALOX5 (0.53) | GAAALOX5ALDH1A1HPGDCYP3A4 | |
| SCHEMBL11334230 | 0.80 | ALDH1A1 (0.46) | KMT2AGAAALDH1A1HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL5352595 | 0.78 | ALOX5 (0.51) | ALOX5ALDH1A1HPGDCYP3A4ALOX15 | |
| SCHEMBL18640589 | 0.76 | ALDH1A1 (0.44) | KMT2AGAAALDH1A1HPGDMEN1 | |
| SCHEMBL11011624 | 0.75 | ALDH1A1 (0.48) | KMT2AALOX5ALDH1A1HPGDCYP3A4 | |
| SCHEMBL8146532 | 0.75 | ALDH1A1 (0.54) | KMT2AGAAALOX5ALDH1A1HPGD | |
| SCHEMBL2100645 | 0.74 | ALOX5 (0.51) | KMT2AALOX5ALDH1A1HPGDCYP3A4 | |
| SCHEMBL236223 | 0.73 | ALDH1A1 (0.54) | KMT2AALOX5ALDH1A1HPGDALOX15 | |
| SCHEMBL11234382 | 0.73 | ALDH1A1 (0.50) | KMT2AALOX5ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582304-B1 | Methods of producing amino butene derivatives | FUJIREBIO KK (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | disclosed |
| US-4837316-A | ANTIULCER AGENTS | FUJIREBIO KABUSHIKI KAISHA (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0214823-A2 | Alkylamide derivatives with H2-receptor antagonistic and cytoprotective action | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1987-03-18 | — | — | EP | disclosed |