Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.49 |
| ▸ | PDE9A | O76083 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554950 | 0.86 | PDE5A (0.44) | PDE5APDE9AALDH1A1GAAKDM4E | |
| SCHEMBL8557792 | 0.85 | PDE5A (0.47) | PDE5APDE9APOLBALDH1A1NPBWR1 | |
| SCHEMBL7505355 | 0.84 | PDE5A (0.52) | PDE5APDE9APOLBALDH1A1PIN1 | |
| SCHEMBL31328139 | 0.84 | PDE5A (0.52) | PDE5APDE9APOLBALDH1A1PIN1 | |
| SCHEMBL8553493 | 0.83 | PDE9A (0.58) | PDE5APDE9AALDH1A1NPBWR1KDM4E | |
| SCHEMBL8557475 | 0.81 | PDE9A (0.49) | PDE5APDE9AALDH1A1PIN1MAPT | |
| SCHEMBL7510573 | 0.81 | PDE5A (0.50) | PDE5APDE9AALDH1A1PIN1MAPT | |
| SCHEMBL7508944 | 0.79 | PDE5A (0.45) | PDE5APDE9AKMT2AMEN1TNKS | |
| SCHEMBL8557199 | 0.79 | PDE5A (0.43) | PDE5APDE9AALDH1A1GAAKDM4E | |
| SCHEMBL7504242 | 0.78 | PDE5A (0.48) | PDE5APDE9AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | claimed |