Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 4/20 | 0.58 |
| ▸ | PDE5A | O76074 | 3/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558570 | 0.89 | KDM4E (0.48) | PDE9APDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL8554829 | 0.85 | PDE9A (0.61) | PDE9APDE5ATNKSPARP1PARP2 | |
| SCHEMBL8555764 | 0.83 | PDE5A (0.49) | PDE9APDE5ATNKSPARP1PARP2 | |
| SCHEMBL8557792 | 0.80 | PDE5A (0.47) | PDE9APDE5ATNKSPARP1PARP2 | |
| SCHEMBL8554950 | 0.79 | PDE5A (0.44) | PDE9APDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL9080896 | 0.78 | PDE9A (0.70) | PDE9APDE5ATNKSPARP1PARP2 | |
| SCHEMBL8557199 | 0.77 | PDE5A (0.43) | PDE9APDE5AKDM4EALDH1A1HPGD | |
| SCHEMBL8554724 | 0.75 | PDE5A (0.48) | PDE9APDE5ATNKSPARP1PARP2 | |
| SCHEMBL3581407 | 0.75 | PDE9A (0.69) | PDE9APDE5APPARGPPARAMEN1 | |
| SCHEMBL3491941 | 0.74 | PDE9A (1.00) | PDE9APDE5ATNKSPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | claimed |
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |