SCHEMBL8556068

SCHEMBL8556068

O=[N+]([O-])c1ccc(O)c(N=Nc2ccccc2O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.57
KMT2A Q03164 6/20 0.57
MAPT P10636 5/20 0.57
ALDH1A1 P00352 5/20 0.57
KDM4E B2RXH2 3/20 0.57
POLB P06746 3/20 0.57
SMN1; SMN2 Q16637 4/20 0.53
HTT P42858 4/20 0.53
LMNA P02545 3/20 0.53
NPC1 O15118 1/20 0.53
HPGD P15428 2/20 0.51
GPR35 Q9HC97 2/20 0.51
TSHR P16473 2/20 0.51
TP53 P04637 1/20 0.51
MAPK1 P28482 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
GAA P10253 1/20 0.50
THRB P10828 1/20 0.50
PSMD14 O00487 1/20 0.49
KCNMA1 Q12791 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31307193 1.00 MEN1 (0.57) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL10898315 1.00 MEN1 (0.57) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL28002467 0.90 MEN1 (0.59) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL11303620 0.87 ALDH1A1 (0.56) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL5306997 0.87 ALDH1A1 (0.56) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL11303617 0.87 ALDH1A1 (0.56) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL8851788 0.86 ALDH1A1 (0.56) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL8851790 0.86 ALDH1A1 (0.56) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL11693093 0.84 ALDH1A1 (0.73) MEN1KMT2AMAPTALDH1A1KDM4E
SCHEMBL5665461 0.84 ALDH1A1 (0.73) MEN1KMT2AMAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104371422-A Ink-jet printer ink HUNAN TENVEE INFORMATION TECHNOLOGY CO LTD 2015-02-25 CN disclosed
EP-0572599-B1 ION-SENSITIVE DYES KODAK LTD (GB) 1998-06-17 EP disclosed
US-5641684-A Ion-sensitive dyes JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) 1997-06-24 US disclosed
EP-0572599-A1 ION-SENSITIVE DYES KODAK LIMITED (GB) 1993-12-08 EP disclosed
WO-1993012428-A1 ION-SENSITIVE DYES KODAK LIMITED (GB) 1993-06-24 WO disclosed
EP-0059958-B1 PROCESS FOR PRODUCING POLYPHENYLENE OXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-06-04 EP disclosed
US-4385168-A FROM OXIDATIVE POLYMERIZATION OF PHENOLIC MONOMER IN PRESENCE OF MANGANIUM SALT AND HYDROXYAZO AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-24 US disclosed
EP-0059958-A1 Process for producing polyphenylene oxide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-09-15 EP disclosed