Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 4/20 | 0.71 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.71 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29768314 | 0.84 | PRCP (1.00) | PRCPSLC22A1ADRB2OPRM1SMN1; SMN2 | |
| SCHEMBL5812041 | 0.84 | PRCP (1.00) | PRCPSLC22A1ADRB2OPRM1SMN1; SMN2 | |
| SCHEMBL4160731 | 0.84 | PRCP (1.00) | PRCPSLC22A1ADRB2OPRM1SMN1; SMN2 | |
| SCHEMBL5284097 | 0.84 | PRCP (1.00) | PRCPSLC22A1ADRB2OPRM1SMN1; SMN2 | |
| Water SCHEMBL28203568 | 0.82 | PRCP (0.97) | PRCPSLC22A1ADRB2OPRM1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8823234 | 0.82 | PRCP (0.97) | PRCPSLC22A1ADRB2OPRM1SMN1; SMN2 | |
| SCHEMBL17361886 | 0.77 | KDM4C (0.60) | PRCPSLC22A1KDM4CRECQLOPRM1 | |
| SCHEMBL30199336 | 0.77 | CHRM2 (0.47) | PRCPSLC22A1KDM4CRECQLGSK3B | |
| Urea SCHEMBL28457637 | 0.76 | PRCP (0.83) | PRCPSLC22A1ADRB2OPRM1SMN1; SMN2 | |
| SCHEMBL10728169 | 0.75 | PRCP (0.77) | PRCPSLC22A1ADRB2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0617022-A1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |