Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559205 | 0.93 | MAOA (0.32) | PDK2MAOA | |
| SCHEMBL8558444 | 0.92 | SIRT2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8558038 | 0.89 | PRKAB2 (0.32) | PDK2EPHX2MAOA | |
| SCHEMBL8555358 | 0.84 | KMT2A (0.30) | PDK2 | |
| SCHEMBL8554692 | 0.84 | SIRT2 (0.31) | PDK2 | |
| SCHEMBL8554543 | 0.83 | MAOA (0.33) | PDK2MAOA | |
| Hydrochloric Acid SCHEMBL8559176 | 0.82 | MAOA (0.32) | PDK2MAOA | |
| Hydrochloric Acid SCHEMBL8556918 | 0.81 | SIRT2 (0.32) | — | |
| SCHEMBL8555171 | 0.81 | SIRT2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8560129 | 0.81 | SIRT2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653426-B1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5510366-A | INOTROPIC, ANTIARRHYMTHMIA AGENTS, VASODILATORS | KOWA CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0653426-A1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA COMPANY, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |