SCHEMBL8556424

SCHEMBL8556424

NC(=O)NN1C(=O)C=CC1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
MGLL Q99685 1/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TSHR P16473 2/20 0.30
NFKB1 P19838 2/20 0.30
CYP1A2 P05177 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
CA2 P00918 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA5A P35218 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5053834 0.78 GAA (0.31) GAAGSK3AGSK3BMGLL
SCHEMBL9809715 0.78 GAA (0.31) GAAGSK3AGSK3BMGLLLMNA
SCHEMBL9193351 0.77 GAA (0.38) GAAGSK3AGSK3BMGLLALDH1A1
SCHEMBL12795884 0.75 L3MBTL1 (0.52) GAAGSK3AGSK3BMGLLLMNA
SCHEMBL24312050 0.75 CA1 (0.35) LMNAALDH1A1MAPTHPGDNPSR1
SCHEMBL22970761 0.70 NPC1 (0.34) GAAGSK3AGSK3BMGLLLMNA
SCHEMBL2539135 0.70 ALDH1A1 (0.42) GAAGSK3AGSK3BMGLLLMNA
SCHEMBL21346936 0.70 L3MBTL1 (0.47) GAAGSK3AGSK3BMGLLLMNA
SCHEMBL20845620 0.70 ALDH1A1 (0.31) ALDH1A1HPGDCYP1A2BLM
SCHEMBL18767287 0.70 L3MBTL1 (0.40) GAAGSK3AGSK3BMGLLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5665852-A USEFUL IN POWDER COATING COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 1997-09-09 US claimed
JP-58088360-A None JP disclosed
CN-1243701-A Use of cholesterol liquid crystal composition in cosmetics and pharmaceutical preparation BASF AG (DE) 2000-02-09 CN disclosed
EP-0830421-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP disclosed
US-5665852-A USEFUL IN POWDER COATING COMPOSITIONS CYTEC TECHNOLOGY CORP. (US) 1997-09-09 US disclosed
WO-1996040825-A1 MODIFIED AMINO CROSSLINKING AGENTS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed
JP-S5888360-A PREPARATION OF N-SUBSTITUTED AMINOMALEIMIDE COMPOUND UBE IND LTD 1983-05-26 JP disclosed