⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556470 | 1.00 | — | — | |
| SCHEMBL8315506 | 0.90 | LMNA (0.31) | — | |
| SCHEMBL8315510 | 0.90 | LMNA (0.31) | — | |
| SCHEMBL8596555 | 0.86 | — | — | |
| SCHEMBL8596558 | 0.86 | — | — | |
| SCHEMBL12812576 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL8312546 | 0.80 | LMNA (0.31) | — | |
| SCHEMBL8312545 | 0.80 | LMNA (0.31) | — | |
| SCHEMBL8749383 | 0.80 | LMNA (0.33) | — | |
| SCHEMBL8749378 | 0.80 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548923-B1 | Antiallergic, antiinflammatory and anti-PAF pyridazine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-07-08 | — | — | EP | disclosed |
| US-5369104-A | Antiasthmatic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-29 | — | — | US | disclosed |
| EP-0548923-A2 | Antiallergic, antiinflammatory and anti-PAF pyridazine compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |