SCHEMBL4951980

SCHEMBL4951980

O=C1CCC(C(=O)CO)O1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.40
CA9 Q16790 1/20 0.40
CYP1A2 P05177 2/20 0.34
PRKCA P17252 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17822545 0.82 CA1 (0.43) CA1CA9CYP1A2PRKCA
SCHEMBL19388490 0.82 CA1 (0.43) CA1CA9CYP1A2PRKCA
SCHEMBL19919867 0.82 CA1 (0.43) CA1CA9CYP1A2PRKCA
SCHEMBL8556521 0.82 CA1 (0.39) CA1CA9CYP1A2PRKCA
SCHEMBL9464860 0.82 CA1 (0.39) CA1CA9CYP1A2PRKCA
SCHEMBL19388489 0.79 CYP1A2 (0.42) CA1CA9CYP1A2PRKCA
SCHEMBL5004697 0.78
SCHEMBL7963430 0.78
SCHEMBL17831604 0.78
SCHEMBL27920507 0.78 CA1 (0.46) CA1CA9CYP1A2PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2643326-B1 Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro[2,3-b]furan-3-ol MYLAN LAB LTD (IN) 2016-09-14 EP disclosed
US-8841467-B2 Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro [2, 3-b] furan-3-ol MYLAN LABORATORIES LIMITED (IN) 2014-09-23 US disclosed
EP-2643326-A1 PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B]FURAN-3-OL Mylan Laboratories, Limited (IN) 2013-10-02 EP disclosed
US-20130244297-A1 PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B] FURAN-3-OL Mylan Laboratories Ltd. (IN) 2013-09-19 US disclosed
WO-2012070057-A1 PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B] FURAN-3-OL MATRIX LABORATORIES LTD (IN) 2012-05-31 WO disclosed
WO-2008034598-A1 METHOD FOR THE SYNTHESIS OF HEXAHYDROFURO (2, 3-B) FURAN-3-OL COMPOUNDS DSM IP ASSETS B.V. (NL) 2008-03-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130244297-A1 PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B] FURAN-3-OL HPD, HAAO, DHRS9 CA1 2054/4885CA9 1796/4885CYP1A2 249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.