Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16449635 | 0.83 | KMT2A (0.45) | KMT2AMEN1PRNPALDH1A1L3MBTL1 | |
| SCHEMBL28029269 | 0.82 | MAPT (0.49) | KMT2AMEN1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6945665 | 0.82 | MGAM (0.47) | KMT2AMEN1PRNPALDH1A1KDM4E | |
| SCHEMBL16449537 | 0.81 | KMT2A (0.48) | KMT2AMEN1PRNPALDH1A1L3MBTL1 | |
| SCHEMBL8798394 | 0.80 | ALDH1A1 (0.68) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6601697 | 0.79 | ALDH1A1 (0.70) | KMT2AMEN1PRNPALDH1A1L3MBTL1 | |
| SCHEMBL4266167 | 0.78 | MAPT (0.49) | KMT2AMEN1PRNPALDH1A1L3MBTL1 | |
| SCHEMBL28667841 | 0.78 | MEN1 (0.46) | KMT2AMEN1PRNPALDH1A1KDM4E | |
| SCHEMBL10709882 | 0.78 | ELANE (0.41) | KMT2AMEN1PRNPALDH1A1KDM4E | |
| SCHEMBL11310453 | 0.78 | TSHR (0.56) | KMT2AMEN1PRNPALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109331862-A | A kind of propenal aldehyde acetal/aniline reaction prepares catalyst of quinoline and preparation method thereof | 湖南理工学院 | 2019-02-15 | — | — | CN | disclosed |
| EP-0529452-B1 | 1,7-Condensed 3-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SOLVAY PHARM GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| EP-0529452-A2 | 1,7-Condensed 2-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |