Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71077 | 0.88 | — | — | |
| SCHEMBL37816440 | 0.88 | — | — | |
| Formaldehyde SCHEMBL28567367 | 0.86 | TSHR (0.54) | TSHRALDH1A1CA1CA2LMNA | |
| SCHEMBL25434481 | 0.85 | TSHR (0.59) | TSHRALDH1A1CA1CA2LMNA | |
| Iodide SCHEMBL7156385 | 0.85 | TSHR (0.59) | TSHRALDH1A1CA1CA2LMNA | |
| Pyrogallol SCHEMBL225781 | 0.83 | CA1 (0.71) | THRBALDH1A1CA1CA2LMNA | |
| SCHEMBL1237641 | 0.76 | THRB (0.71) | TSHRTHRBALDH1A1CA1CA2 | |
| SCHEMBL29593170 | 0.76 | THRB (0.71) | TSHRTHRBALDH1A1CA1CA2 | |
| SCHEMBL30779693 | 0.76 | KLKB1 (0.51) | TSHRTHRBALDH1A1HPGDALOX15 | |
| SCHEMBL421701 | 0.76 | KLKB1 (0.51) | TSHRTHRBALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698026-B1 | METHOD FOR PREPARING ERYTHRURONOLACTONE | VIRGINIA TECH INTELL PROP (US) | 1998-07-15 | — | — | EP | disclosed |
| EP-0698026-A1 | METHOD FOR PREPARING ERYTHRURONOLACTONE | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5442079-A | Method for preparing erythruronolactone | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1994026748-A1 | METHOD FOR PREPARING ERYTHRURONOLACTONE | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1994-11-24 | — | — | WO | disclosed |