Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364014 | 0.74 | TDP1 (0.43) | TDP1L3MBTL1ALDH1A1KDM4EATM | |
| SCHEMBL4838463 | 0.73 | MPI (0.39) | ALDH1A1LMNAHPGD | |
| SCHEMBL29365992 | 0.73 | GOT1 (0.62) | MEN1GFERKMT2ATDP1L3MBTL1 | |
| SCHEMBL345211 | 0.73 | GOT1 (0.62) | MEN1GFERKMT2ATDP1L3MBTL1 | |
| SCHEMBL11816309 | 0.70 | TLR7 (0.37) | MEN1GFERKMT2ATDP1L3MBTL1 | |
| SCHEMBL24855721 | 0.69 | KDM4E (0.80) | MEN1KMT2AGOT1ALDH1A1KDM4E | |
| SCHEMBL2534009 | 0.69 | TDP1 (0.69) | KMT2ATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL30013732 | 0.69 | TDP1 (0.69) | KMT2ATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL24252315 | 0.69 | POLB (0.33) | HTT | |
| SCHEMBL30467658 | 0.69 | POLB (0.33) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0534443-B1 | 3,6-Disubstituted pyridazine derivatives | MITSUBISHI CHEM CORP (JP) | 1998-12-30 | — | — | EP | disclosed |
| US-5462941-A | 1-(cyclohexylalkylamino)-4-(phenyl, thienyl, or furyl) phthalazines; anti-platelet agglutination agents for treatment or prevention of cerebro- or cardiovascular disorders | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0534443-A1 | 3,6-Disubstituted pyridazine derivatives | Mitsubishi Chemical Corporation (JP) | 1993-03-31 | — | — | EP | disclosed |