Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GOT1 | P17174 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29365992 | 1.00 | GOT1 (0.62) | GOT1MEN1KMT2AGFERALDH1A1 | |
| Bicarbonate SCHEMBL11022555 | 0.87 | GOT1 (0.52) | GOT1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL2126344 | 0.84 | GOT1 (0.50) | GOT1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL30645164 | 0.84 | MEN1 (0.50) | GOT1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL2306302 | 0.84 | MEN1 (0.50) | GOT1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL2020349 | 0.84 | KDM4E (0.71) | GOT1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL10906806 | 0.83 | GOT1 (0.48) | GOT1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL11490177 | 0.81 | GOT1 (0.47) | GOT1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL29537275 | 0.81 | MAPT (0.49) | GOT1MEN1KMT2AGFERALDH1A1 | |
| SCHEMBL580414 | 0.81 | MAPT (0.49) | GOT1MEN1KMT2AGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 936 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119433974-A | Preparation method of crosslinked cellulose fiber | 中国纺织科学研究院有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-220829026-U | 1, 4-Dichlorophthalazine high-efficiency drying device | 徐州彰梁生化科技有限公司 | 2024-04-23 | — | — | CN | claimed |
| CN-219111133-U | Waste gas treatment device in 1, 4-dichlorophthalazine production | 徐州彰梁生化科技有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-116159594-A | Application of pyridinium small molecule as photocatalyst in alcohol and amine series reaction | 北京理工大学 | 2023-05-26 | — | — | CN | claimed |
| US-11649232-B2 | Synthetic dimeric cinchona alkaloids against cancer | Ares Pharmaceuticals, LLC (US) | 2023-05-16 | — | — | US | claimed |
| US-20220372029-A1 | SYNTHETIC DIMERIC CINCHONA ALKALOIDS AGAINST CANCER | Ares Pharmaceuticals, LLC (US) | 2022-11-24 | — | — | US | claimed |
| CN-114773352-A | Process for preparing substituted nicotinamides | 上海赛默罗生物科技有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-110156696-B | Preparation method of 1, 4-dichlorophthalazine | 海门瑞一医药科技有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-113979950-A | Preparation and performance research of aggregation-induced emission molecule based on phthalazine | 长春工业大学 | 2022-01-28 | — | — | CN | claimed |
| CN-110305068-A | Method for continuously preparing 1, 4-dichlorophthalazine by using microchannel reactor | 中昊(大连)化工研究设计院有限公司 | 2019-10-08 | — | — | CN | claimed |
| US-5100471-A | Liquid ink compositions | XEROX CORPORATION (US) | 1992-03-31 | — | — | US | claimed |
| US-5098475-A | Inks with dendrimer colorants | XEROX CORPORATION (US) | 1992-03-24 | — | — | US | claimed |
| EP-0167107-B1 | PROCESS FOR THE MANUFACTURE OF AQUEOUS, FLUID PREPARATIONS OF REACTIVE DYES WITH A LOW SALT CONTENT | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-08 | — | — | EP | claimed |
| US-4877451-A | Ink jet inks containing colored silica particles | XEROX CORPORATION (US) | 1989-10-31 | — | — | US | claimed |
| CN-85105944-B | Tertiary amine catalytic synthesis method of dihydrazino phthalazine sulfate | 武汉化工学院 | 1988-03-23 | — | — | CN | claimed |
| CN-85105944-A | The tertiary amine catalytic synthesis method of dihydrallazine sulphate | — | 1987-03-18 | — | — | CN | claimed |
| EP-0167107-A2 | Process for the manufacture of aqueous, fluid preparations of reactive dyes with a low salt content | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-08 | — | — | EP | claimed |
| EP-0069300-B1 | LIQUID PREPARATIONS OF REACTIVE DYES AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-20 | — | — | EP | claimed |
| US-4443224-A | Liquid reactive dyestuff preparations and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-04-17 | — | — | US | claimed |
| EP-0069300-A1 | Liquid preparations of reactive dyes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649232-B2 | Synthetic dimeric cinchona alkaloids against cancer | BAD, MCL1, BCL9 | GOT1 694/4885MEN1 140/4885KMT2A 462/4885 |
| US-20220372029-A1 | SYNTHETIC DIMERIC CINCHONA ALKALOIDS AGAINST CANCER | BAD, MCL1, BCL9 | GOT1 694/4885MEN1 140/4885KMT2A 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.