Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551496 | 0.85 | NOTUM (0.34) | NOTUMTRPA1SCN5ASCN9ADHODH | |
| SCHEMBL8554505 | 0.85 | GABRP (0.36) | NOTUM | |
| SCHEMBL8554641 | 0.83 | NOTUM (0.35) | NOTUMTRPA1SCN5ASCN9ADHODH | |
| SCHEMBL8552473 | 0.81 | — | — | |
| SCHEMBL8553570 | 0.78 | NOTUM (0.34) | NOTUMTRPA1SCN5ASCN9ADHODH | |
| SCHEMBL8399396 | 0.77 | NOTUM (0.36) | NOTUMTRPA1SCN5ASCN9ADHODH | |
| SCHEMBL8399379 | 0.77 | NOTUM (0.36) | NOTUMTRPA1SCN5ASCN9ADHODH | |
| SCHEMBL8556443 | 0.76 | NOTUM (0.33) | NOTUMTRPA1SCN5ASCN9A | |
| SCHEMBL8550923 | 0.71 | GABRP (0.34) | NOTUM | |
| SCHEMBL8555613 | 0.70 | GABRP (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871617-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997007102-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC (US) | 1997-02-27 | — | — | WO | disclosed |