SCHEMBL8556751

SCHEMBL8556751

NCC(=O)Oc1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
MAPT P10636 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
ALDH1A1 P00352 3/20 0.54
CYP1A2 P05177 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
AGXT P21549 2/20 0.53
PTPN7 P35236 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
KDM4E B2RXH2 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MMP1 P03956 2/20 0.46
MMP12 P39900 1/20 0.46
PPARG P37231 2/20 0.46
HTT P42858 1/20 0.46
NCOA2 Q15596 1/20 0.46
NCOA1 Q15788 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
NR2E3 Q9Y5X4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15744796 0.85 KMT2A (0.59) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL27631735 0.83 KMT2A (0.58) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL6666008 0.82 ALDH1A1 (0.44) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL28110718 0.81 KMT2A (0.56) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL10780307 0.81 KMT2A (0.56) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL8401001 0.81 KMT2A (0.61) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL11467623 0.81 KMT2A (0.56) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL4441141 0.81 PDGFRB (0.61) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL38659578 0.81 PDGFRB (0.61) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL17616870 0.80 KMT2A (0.60) KMT2AMEN1MAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109232396-B Amide pyridine derivative and application thereof 聊城大学 2020-07-03 CN disclosed
CN-100436406-C Process for producing optically active bisamidoalcohol compound SUMITOMO CHEMICAL CO (JP) 2008-11-26 CN disclosed
CN-100408553-C Method for producing optically active cycloalkylidenebisoxazoline compound and intermediate of the same SUMITOMO CHEMICAL CO (JP) 2008-08-06 CN disclosed
CN-1898196-A Process for producing optically active cycloalkylidenebisoxazoline compound and intermediate of the compound SUMITOMO CHEMICAL CO (JP) 2007-01-17 CN disclosed
CN-1898193-A Method for producing optically active bisamidealcohol compound SUMITOMO CHEMICAL CO (JP) 2007-01-17 CN disclosed
EP-0848957-A1 Fas LIGAND SOLUBILIZATION INHIBITOR KANEBO LTD. (JP) 1998-06-24 EP disclosed