Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27631735 | 0.86 | KMT2A (0.58) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL28010902 | 0.85 | TDP1 (0.47) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL11467623 | 0.85 | KMT2A (0.56) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL8556751 | 0.85 | KMT2A (0.56) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL8401001 | 0.85 | KMT2A (0.61) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL4441141 | 0.85 | PDGFRB (0.61) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL38659578 | 0.85 | PDGFRB (0.61) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL10780307 | 0.85 | KMT2A (0.56) | KMT2AMEN1MAPTTDP1KDM4E | |
| SCHEMBL28110718 | 0.85 | KMT2A (0.56) | KMT2AMEN1MAPTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL28858265 | 0.83 | PDGFRB (0.59) | KMT2AMEN1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2017-03-09 | — | — | US | disclosed |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2017-03-09 | — | — | US | disclosed |
| US-9532973-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-01-03 | — | — | US | disclosed |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2015-07-02 | — | — | US | disclosed |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2015-07-02 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, KLK1, SERPINC1 | KMT2A 3807/4885MEN1 913/4885MAPT 4804/4885 |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, SERPINC1, KLK1 | KMT2A 3749/4885MEN1 904/4885MAPT 4807/4885 |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, SERPINC1, KLK1 | KMT2A 3749/4885MEN1 904/4885MAPT 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.