Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RHEB | Q15382 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555586 | 0.89 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8556967 | 0.86 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8555784 | 0.86 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8551888 | 0.83 | NPY1R (0.48) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8554085 | 0.79 | NPY1R (0.49) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8555194 | 0.78 | SMN1; SMN2 (0.47) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8556385 | 0.77 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8551977 | 0.75 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| SCHEMBL8556128 | 0.75 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2POLBTDP1 | |
| Trifluoroacetic Acid SCHEMBL8552498 | 0.73 | NPY1R (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |