Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556818 | 0.83 | RAB9A (0.47) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL8555586 | 0.83 | RAB9A (0.47) | NPC1POLBRAB9ASMN1; SMN2TDP1 | |
| SCHEMBL8554085 | 0.77 | NPY1R (0.49) | NPY1RNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL8555457 | 0.74 | DGAT2 (0.37) | POLB | |
| SCHEMBL7690344 | 0.72 | NPY1R (0.47) | NPY1RHRH3 | |
| Trifluoroacetic Acid SCHEMBL8552498 | 0.71 | NPY1R (0.44) | NPY1R | |
| SCHEMBL8556967 | 0.70 | RAB9A (0.49) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL8551977 | 0.70 | RAB9A (0.49) | KMT2ANPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL8555784 | 0.69 | RAB9A (0.46) | MEN1KMT2ANPC1POLBRAB9A | |
| SCHEMBL8556128 | 0.69 | RAB9A (0.46) | MEN1KMT2ANPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |