Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ACLY | P53396 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674392 | 0.98 | TP53 (0.39) | DBHTP53ACLYCYP3A4IDO1 | |
| SCHEMBL16956209 | 0.92 | TP53 (0.41) | DBHTP53CYP3A4IDO1MEN1 | |
| SCHEMBL9591964 | 0.85 | ACLY (0.49) | ACLYCYP3A4IDO1CYP1A2CYP2C9 | |
| SCHEMBL16958244 | 0.84 | TP53 (0.44) | DBHTP53CYP3A4IDO1MEN1 | |
| SCHEMBL10919386 | 0.82 | IDO1 (0.50) | ACLYCYP3A4IDO1CYP1A2CYP2C9 | |
| SCHEMBL11239272 | 0.81 | SIRT2 (0.38) | DBHTP53ACLYCYP3A4IDO1 | |
| SCHEMBL1310459 | 0.81 | TYR (0.44) | TP53CYP3A4MEN1MAPTALOX15 | |
| SCHEMBL5189692 | 0.81 | TYR (0.44) | TP53CYP3A4MEN1MAPTALOX15 | |
| SCHEMBL5900913 | 0.81 | TYR (0.44) | TP53CYP3A4MEN1MAPTALOX15 | |
| SCHEMBL11336119 | 0.80 | HPGD (0.40) | DBHTP53ACLYCYP3A4USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923370-A2 | METHOD OF TREATING AND DIAGNOSING SLEEP DISORDERED BREATHING AND MEANS FOR CARRYING OUT THE METHOD | A+ Science Invest AB (SE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1997022339-A1 | METHOD OF TREATING AND DIAGNOSING SLEEP DISORDERED BREATHING AND MEANS FOR CARRYING OUT THE METHOD | HEDNER JAN (SE) | 1997-06-26 | — | — | WO | disclosed |