SCHEMBL8557115

SCHEMBL8557115

CCCCc1nc(Oc2c(C)cc(-c3nnn(C)n3)cc2C)cn1C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 1/20 0.32
AGTR2 P50052 1/20 0.32
SPNS2 Q8IVW8 1/20 0.31
TRPV1 Q8NER1 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8555476 0.78
SCHEMBL8556856 0.74 NR1I2 (0.33)
SCHEMBL8556858 0.72
SCHEMBL8551731 0.71 SMN1; SMN2 (0.31)
SCHEMBL8992126 0.70 NPC1 (0.32) TRPV1
SCHEMBL8557109 0.70 KMT2A (0.36)
SCHEMBL8605399 0.69 NR1I2 (0.36)
SCHEMBL8992087 0.69 NPC1 (0.31) TRPV1
SCHEMBL8603712 0.69 NR1I2 (0.37)
SCHEMBL8665484 0.68 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5846986-A Therapeutic phenoxyalkylazoles and phenoxyalkylazines SANOFI (FR) 1998-12-08 US disclosed
US-5721261-A TREATING PICORNAVIRUS INFECTIONS SANOFI PHARMACEUTICALS, INC. (US) 1998-02-24 US disclosed