Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992087 | 0.79 | NPC1 (0.31) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8551731 | 0.76 | SMN1; SMN2 (0.31) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8556858 | 0.76 | — | — | |
| SCHEMBL8824405 | 0.71 | NPC1 (0.34) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8824414 | 0.70 | NR1I2 (0.39) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8992121 | 0.70 | BRD4 (0.37) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8557115 | 0.70 | AGTR1 (0.32) | TRPV1 | |
| SCHEMBL8665484 | 0.67 | KDM4E (0.31) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8553777 | 0.67 | SMN1; SMN2 (0.33) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8603712 | 0.67 | NR1I2 (0.37) | NPC1NFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514679-A | TREATMENT OF PICORNAVIRUS INFECTIONS | STERLING WINTHROP INC. (US) | 1996-05-07 | — | — | US | disclosed |