Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556858 | 0.77 | — | — | |
| SCHEMBL8992126 | 0.76 | NPC1 (0.32) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL8552168 | 0.73 | HDAC4 (0.37) | SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8992087 | 0.71 | NPC1 (0.31) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL8557115 | 0.71 | AGTR1 (0.32) | — | |
| SCHEMBL8824405 | 0.68 | NPC1 (0.34) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL9089930 | 0.67 | NR1I2 (0.35) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL8555476 | 0.67 | — | — | |
| SCHEMBL8824414 | 0.67 | NR1I2 (0.39) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 | |
| SCHEMBL8551728 | 0.67 | NR1I2 (0.34) | SMN1; SMN2NPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |