SCHEMBL855728

SCHEMBL855728

CCCCOCC(O[SiH3])(OCCCC)OCCCC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
CES1 P23141 1/20 0.37
CYP3A4 P08684 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
HPGD P15428 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4145527 0.89 TSHR (0.42) TSHRCES1CYP3A4SMN1; SMN2HPGD
SCHEMBL7591304 0.82 CES1 (0.48) TSHRCES1MEN1THRBHTT
SCHEMBL5031070 0.82 HSD17B10 (0.30)
SCHEMBL16909992 0.82 ADRB2 (0.35) TSHRCYP3A4ADRB2ADRB1ADRB3
SCHEMBL11012630 0.80 CYP3A4 (0.34) TSHRCYP3A4ADRB2ADRB1ADRB3
SCHEMBL2858501 0.79 TSHR (0.35) TSHRCES1CYP3A4SMN1; SMN2HPGD
SCHEMBL430961 0.78 TSHR (0.34) TSHRCES1CYP3A4
SCHEMBL37202 0.78 CYP3A4 (0.47) TSHRCES1CYP3A4SMN1; SMN2HPGD
SCHEMBL15809387 0.77 TSHR (0.41) TSHRCES1CYP3A4SMN1; SMN2HPGD
SCHEMBL855727 0.77 ADRB2 (0.35) TSHRCYP3A4SMN1; SMN2HPGDADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10702467-B2 Emulsion containing organosilicon-based portions of hollow spheres L'ORÉAL (FR) 2020-07-07 US claimed
US-20170304183-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'ORÉAL (FR) 2017-10-26 US claimed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US claimed
US-20130224267-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2013-08-29 US claimed
US-20110217346-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2011-09-08 US claimed
EP-1530961-B1 Emulsion containing hollow organosilicon particles OREAL (FR) 2009-08-05 EP claimed
US-20050118218-A1 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2005-06-02 US claimed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP claimed
US-10702467-B2 Emulsion containing organosilicon-based portions of hollow spheres L'ORÉAL (FR) 2020-07-07 US disclosed
EP-3021948-B1 OIL/OIL EMULSIONS CONTAINING PARTICLES WITH A BREAKAGE OF CURVATURE, COMPOSITIONS COMPRISING THEM AND USE OF THE PARTICLES FOR STABILIZING O/O EMULSIONS OREAL (FR) 2019-08-21 EP disclosed
EP-2476719-B1 IRREGULAR-SHAPED MICROPARTICLES, PROCESS FOR PRODUCTION OF IRREGULAR-SHAPED MICROPARTICLES, AND COSMETICS AND RESIN COMPOSITIONS CONTAINING IRREGULAR-SHAPED MICROPARTICLES TAKEMOTO OIL & FAT CO LTD (JP) 2019-01-02 EP disclosed
US-20170304183-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'ORÉAL (FR) 2017-10-26 US disclosed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US disclosed
EP-2462197-B1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF ORÉAL L (FR) 2016-09-21 EP disclosed
US-20050220740-A1 Cosmetic composition comprising concave particles L'OREAL S.A. (FR) 2005-10-06 US disclosed
US-20050220741-A1 Cosmetic composition comprising concave particles L'OREAL S.A. (FR) 2005-10-06 US disclosed
EP-1579841-A1 Cosmetic composition comprising concave particles L'OREAL (FR) 2005-09-28 EP disclosed
EP-1579849-A1 Cosmetic compositions comprising concave particles. L'OREAL (FR) 2005-09-28 EP disclosed
US-20050118218-A1 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2005-06-02 US disclosed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP disclosed