Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087810 | 0.89 | ALDH1A1 (0.34) | ALDH1A1TSHRNOS1HSD17B10KDM4E | |
| SCHEMBL1687706 | 0.82 | KDM4E (0.36) | ALDH1A1TSHRNOS1HSD17B10KDM4E | |
| SCHEMBL5803213 | 0.81 | ALDH1A1 (0.37) | ALDH1A1TSHRNOS1HSD17B10KDM4E | |
| SCHEMBL16357614 | 0.81 | SLC6A2 (0.35) | ALDH1A1TSHRNOS1HSD17B10KDM4E | |
| SCHEMBL24087245 | 0.79 | CTSK (0.37) | ALDH1A1KDM4ELMNAMAPKAPK2HRH1 | |
| SCHEMBL20694152 | 0.78 | SLC6A2 (0.48) | KDM4ELMNAMAPKAPK2HRH1SLC6A2 | |
| SCHEMBL24087824 | 0.78 | KDM4E (0.35) | ALDH1A1TSHRNOS1HSD17B10KDM4E | |
| SCHEMBL4312352 | 0.78 | — | — | |
| SCHEMBL1532491 | 0.78 | — | — | |
| SCHEMBL5475949 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |