Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL8561436 | 1.00 | RAD52 (0.34) | RAD52TAAR1POLBSIGMAR1GLA | |
| SCHEMBL8555780 | 0.98 | RAD52 (0.35) | RAD52TAAR1POLBSIGMAR1GLA | |
| Hydrazine SCHEMBL8554894 | 0.98 | RAD52 (0.35) | RAD52TAAR1POLBGLATDP1 | |
| SCHEMBL8560784 | 0.98 | RAD52 (0.35) | RAD52TAAR1POLBSIGMAR1GLA | |
| SCHEMBL8553122 | 0.97 | RAD52 (0.35) | RAD52TAAR1POLBGLATDP1 | |
| Hydrazine SCHEMBL8552818 | 0.93 | TAAR1 (0.34) | RAD52TAAR1 | |
| SCHEMBL6186423 | 0.91 | TAAR1 (0.35) | RAD52TAAR1 | |
| Hydrazine SCHEMBL8553287 | 0.86 | TAAR1 (0.30) | TAAR1 | |
| SCHEMBL782154 | 0.84 | TAAR1 (0.31) | TAAR1 | |
| SCHEMBL5770282 | 0.83 | TAAR1 (0.42) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |