Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186423 | 0.98 | TAAR1 (0.35) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| Hydrazine SCHEMBL8554894 | 0.95 | RAD52 (0.35) | TAAR1RAD52 | |
| Hydrazine SCHEMBL8561436 | 0.93 | RAD52 (0.34) | TAAR1RAD52 | |
| Hydrazine SCHEMBL8557324 | 0.93 | RAD52 (0.34) | TAAR1RAD52 | |
| SCHEMBL8553122 | 0.93 | RAD52 (0.35) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8555780 | 0.91 | RAD52 (0.35) | TAAR1RAD52 | |
| SCHEMBL8560784 | 0.91 | RAD52 (0.35) | TAAR1RAD52 | |
| Hydrazine SCHEMBL8553287 | 0.89 | TAAR1 (0.30) | TAAR1 | |
| SCHEMBL782154 | 0.87 | TAAR1 (0.31) | TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6284637 | 0.80 | TAAR1 (0.43) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |