Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL8552818 | 0.98 | TAAR1 (0.34) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8553122 | 0.95 | RAD52 (0.35) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| Hydrazine SCHEMBL8554894 | 0.93 | RAD52 (0.35) | TAAR1RAD52 | |
| SCHEMBL8555780 | 0.93 | RAD52 (0.35) | TAAR1RAD52 | |
| SCHEMBL8560784 | 0.93 | RAD52 (0.35) | TAAR1RAD52 | |
| Hydrazine SCHEMBL8557324 | 0.91 | RAD52 (0.34) | TAAR1RAD52 | |
| Hydrazine SCHEMBL8561436 | 0.91 | RAD52 (0.34) | TAAR1RAD52 | |
| SCHEMBL782154 | 0.89 | TAAR1 (0.31) | TAAR1SLC6A2SLC6A4SLC6A3 | |
| Hydrazine SCHEMBL8553287 | 0.87 | TAAR1 (0.30) | TAAR1 | |
| SCHEMBL6284637 | 0.81 | TAAR1 (0.43) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721200-A | REACTING OLEFINIC COPLYMER WITH UNSATURATED ACYLATING AGENT TO FROM A GRAFT COPOLYMER AND REDUCING MOLECULAR WEIGHT, REACTING GRAFTED COPOLYMER WITH AMINO-ALCOHOL COMPOUND | DSM COPOLYMER, INC. (US) | 1998-02-24 | — | — | US | claimed |
| US-5474694-A | Dispersant additive which is an modified alpha-olefin polymer | TEXACO INC. (US) | 1995-12-12 | — | — | US | claimed |
| EP-0515152-A1 | Dispersant additive and lubricating oil composition containing same | TEXACO DEVELOPMENT CORPORATION (US) | 1992-11-25 | — | — | EP | claimed |
| US-5162086-A | Amino-phenothiazine modified graft polymer | TEXACO INC. (US) | 1992-11-10 | — | — | US | claimed |
| EP-1537087-B1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2012-11-28 | — | — | EP | disclosed |
| CN-1982316-A | Novel aminoindazole derivatives as medicaments and pharmaceutical compositions including them | AVENTIS PHARMA SA (FR) | 2007-06-20 | — | — | CN | disclosed |
| CN-1678589-A | Novel aminoindazole derivatives as medicaments and pharmaceutical compositions containing them | AVENTIS PHARMA SA (FR) | 2005-10-05 | — | — | CN | disclosed |
| EP-1537087-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022544-A1 | NOVEL AMINOINDAZOLE DERIVATIVES AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2004-03-18 | — | — | WO | disclosed |
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |
| US-5760098-A | FORMING POLYURETHANES FROM POLYISOCYANATES BY CARBAMATE PROMOTED POLYMERIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |
| EP-0758659-A1 | Process for the preparation of low emission polyurethane moulding and composite materials and their use | BAYER AG (DE) | 1997-02-19 | — | — | EP | disclosed |
| US-5424451-A | Used as cholinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5302593-A | Aminoalkylcarbamic esters of eseroline suitable for use as chlorinesterase activity inhibitors | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1994-04-12 | — | — | US | disclosed |
| EP-0575954-A1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-12-29 | — | — | EP | disclosed |