Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 11/20 | 0.54 |
| ▸ | RARB | P10826 | 11/20 | 0.54 |
| ▸ | RARG | P13631 | 10/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.42 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510939 | 0.85 | RARA (0.42) | RARARARBRARGRXRARXRB | |
| SCHEMBL8511470 | 0.85 | RARB (0.64) | RARARARBRARGHRH3RXRA | |
| SCHEMBL9184946 | 0.80 | ABCB1 (0.58) | RARARARBRARGRXRA | |
| SCHEMBL25637844 | 0.80 | RARB (0.71) | RARARARBRARGRXRARXRB | |
| SCHEMBL9483603 | 0.79 | RARB (0.58) | RARARARBRARGRXRARXRB | |
| SCHEMBL4965729 | 0.78 | RARB (0.69) | RARARARBRARGRXRARXRB | |
| SCHEMBL8675471 | 0.78 | MAOB (0.53) | — | |
| SCHEMBL24808023 | 0.77 | RARB (0.54) | RARARARBRARGRXRARXRB | |
| SCHEMBL24794223 | 0.77 | RARA (0.54) | RARARARBRARGRXRA | |
| SCHEMBL5847673 | 0.77 | RARB (0.58) | RARARARBRARGRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5709867-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-20 | — | — | US | disclosed |