Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557098 | 0.74 | HCRTR1 (0.31) | — | |
| SCHEMBL8558951 | 0.72 | NOTUM (0.33) | — | |
| SCHEMBL8557378 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL8556205 | 0.69 | — | — | |
| Oxalic Acid SCHEMBL9049301 | 0.65 | ACE2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL9704642 | 0.64 | CHRM2 (0.33) | — | |
| SCHEMBL2141020 | 0.63 | MAPK1 (0.43) | HSD17B10 | |
| Oxalic Acid SCHEMBL9049924 | 0.62 | ALDH1A1 (0.31) | — | |
| Oxalic Acid SCHEMBL9703375 | 0.62 | PDK2 (0.35) | — | |
| SCHEMBL23860306 | 0.62 | FAAH (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366304-B1 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1998-04-15 | — | — | EP | claimed |
| US-5166357-A | Nitrogen heterocylic compounds used in treatment of dementia in mammals | BEECHAM GROUP P.L.C. (GB) | 1992-11-24 | — | — | US | claimed |
| EP-0366304-A2 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-05-02 | — | — | EP | claimed |
| EP-0366304-B1 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1998-04-15 | — | — | EP | disclosed |
| US-5166357-A | Nitrogen heterocylic compounds used in treatment of dementia in mammals | BEECHAM GROUP P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0366304-A2 | Heterocyclic derivatives, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1990-05-02 | — | — | EP | disclosed |