Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | GAA | P10253 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703730 | 0.88 | MAPT (0.73) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL1482126 | 0.88 | MAPT (0.73) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL27456657 | 0.87 | MAPT (0.71) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL4118503 | 0.87 | MAPT (0.71) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL3067260 | 0.86 | ALDH1A1 (0.58) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL2943696 | 0.86 | MAPT (0.55) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL2951888 | 0.86 | MAPT (0.55) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL27610366 | 0.86 | MAPT (0.74) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL15127501 | 0.86 | MAPT (0.79) | MAPTGAALMNAKDM4EALDH1A1 | |
| SCHEMBL4116463 | 0.85 | MAPT (0.69) | MAPTGAALMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5795893-A | Fibrinogen receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1998-08-18 | — | — | US | disclosed |