Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558433 | 0.88 | F2 (0.41) | ESR2HDAC6NR1H2BRD4CREBBP | |
| SCHEMBL8556263 | 0.87 | P2RX3 (0.42) | ESR2MAPTKDM4EENPP2GPR119 | |
| SCHEMBL8558435 | 0.81 | TPSAB1 (0.40) | HDAC6MAPTENPP2GRAMD1AGPR119 | |
| SCHEMBL1174513 | 0.74 | HDAC6 (0.72) | ESR2HDAC6NR1H2BRD4CREBBP | |
| SCHEMBL743782 | 0.74 | HDAC6 (0.54) | ESR2HDAC6NR1H2BRD4CREBBP | |
| SCHEMBL8555269 | 0.74 | HDAC6 (0.54) | ESR2HDAC6NR1H2BRD4CREBBP | |
| SCHEMBL6421478 | 0.73 | NR1H2 (0.54) | ESR2HDAC6NR1H2BRD4CREBBP | |
| SCHEMBL978284 | 0.73 | HDAC6 (0.59) | ESR2HDAC6NR1H2BRD4CREBBP | |
| SCHEMBL6422061 | 0.71 | NR1H2 (0.52) | ESR2HDAC6NR1H2BRD4CREBBP | |
| SCHEMBL15166579 | 0.71 | ESR2 (0.50) | ESR2NR1H2MAPTKDM4ENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641770-B1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA CO (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5594004-A | CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641770-A1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-03-08 | — | — | EP | disclosed |