Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114972 | 0.90 | ABCC8 (0.33) | ABCC8KCNJ11MEN1KMT2A | |
| SCHEMBL8128461 | 0.87 | ABCC8 (0.33) | ABCC8KCNJ11MEN1KMT2A | |
| SCHEMBL8557011 | 0.86 | — | — | |
| SCHEMBL3670098 | 0.82 | ABCC8 (0.33) | ABCC8KCNJ11MEN1KMT2A | |
| SCHEMBL8123914 | 0.82 | ABCC8 (0.33) | ABCC8KCNJ11MEN1KMT2A | |
| SCHEMBL8556823 | 0.81 | GRIN2D (0.35) | MEN1KMT2A | |
| SCHEMBL8554470 | 0.81 | GRIN2D (0.32) | MEN1KMT2A | |
| SCHEMBL8122116 | 0.81 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL8127539 | 0.81 | — | — | |
| SCHEMBL8124641 | 0.81 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647137-A4 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF. | UNIV CALIFORNIA WEBER ECKARD (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0647137-A1 | GLYCINE RECEPTOR ANTAGONISTS AND THE USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1995-04-12 | — | — | EP | disclosed |