Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728002 | 0.71 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM5BKDM1A | |
| SCHEMBL9833178 | 0.69 | — | — | |
| SCHEMBL31728290 | 0.68 | MEN1 (0.41) | MEN1KMT2AALDH1A1KDM5BKDM1A | |
| SCHEMBL1742675 | 0.66 | LMNA (0.53) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9679579 | 0.65 | CKS1B (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31727853 | 0.64 | KDM1A (0.41) | MEN1KMT2AALDH1A1KDM5BKDM1A | |
| SCHEMBL8558004 | 0.62 | TSHR (0.33) | KDM5B | |
| SCHEMBL10490335 | 0.62 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9830595 | 0.62 | TSHR (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL8107102 | 0.62 | LMNA (0.40) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537611-B1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOW AGROSCIENCES LLC (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0537611-A1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5177206-A | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-01-05 | — | — | US | disclosed |
| US-5003096-A | Alkylsilylaniline intermediates for herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4910306-A | Combining a sulfonyl halide with N-trialkylsilylaniline | THE DOW CHEMICAL COMPANY (US) | 1990-03-20 | — | — | US | disclosed |